Assisted Reproductive Technology(ART)

Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is an assisted reproductive technology for the diagnosis of a genetic disease in early embryos prior to implantation and pregnancy in an IVF cycle. This technology is effective for aneuploidy screening and the diagnosis of unbalanced inheritance of chromosome abnormalities such as translocations or inversions.

FISH (Fluorescent In situ hybridization) technique

FISH is the most commonly applied method to determine the chromosomal constitution of an embryo. The cells are fixated on glass microscope slides and hybridized with DNA probes. Each of these probes are specific for part of a chromosome, and are labelled with a fluorochrome.

PCR (Polymerase chain Reaction) technique

PCR provides the possibility to obtain a large quantity of copies of a particular stretch of the genome. It makes it suitable for all kinds of genetic diagnosis.